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Start Here: Why This Place Exists
I went back and forth on whether to write this for a long time. Part of me never wanted this community to become another place that just sells access. There are already enough of those. When I started this group it was really just an extension of the conversations I was having anyway. Interesting papers. Questions I couldn’t stop thinking about. Mechanisms that seemed important but weren’t getting much attention. Things I was learning from my own training, my own health, and the people I have the privilege of working with. Somewhere along the way it grew into something much bigger than I expected. That part is exciting. But it also created a problem. A lot of the conversations I actually want to have don’t fit into a social media post. They don’t fit into a reel. And they definitely don’t fit into a comment section. Some topics need an hour. Some need ten. Because understanding something and hearing about something are not the same thing. Most people today know more than they ever have. And yet somehow they are more confused than ever. They have collected protocols, saved posts, screenshots, stacks, peptides, supplements. But if you changed one variable tomorrow, they wouldn’t know what to do next. That is not a criticism. I have been there myself. The deeper I get into this field, the more convinced I become that understanding is the real asset. Not information. Information is cheap now. Understanding is rare. So that is what this place is built around. Not protocols. Not secret compounds. Not some exclusive club. A classroom. We take a topic that matters and pull it apart, piece by piece, until it actually makes sense. We talk about the things everyone is excited about, and the things nobody is paying attention to yet. We bring in smart people who challenge the way I think. We do live Q&As. And I spend real time showing not just what I am doing, but how I am thinking through decisions as they happen. Because that is the skill that transfers. That is the thing that stays useful when the next study comes out and changes the conversation.
HRT
I struggle w hrt. I feel amazing on it. I microdose it. I’m doing a progesterone world or cream either one and a tropical estradiol after an extremely small dose at that dose. I feel amazing except my body. Mainly my stomach is super bloated. You don’t know how to fix this.
Knee joint replacement
In 2021 I was diagnosed with osteoarthritis in my left knee. At age 53 the advice was, keep training to sustain muscle mass and thereby support the knee as much as possible. Further advice was not to operate. A large portion of the cartilage was already gone by then and no magic supplement was going to bring it back. It was all about buying time. Fast forward, the recent diagnoses shows all cartilage on the inner part of the knee is gone. That was to be expected. Slowly over the years I started limping more, difficulty getting up the stairs, having frequent lower back issues and for the past 3 months daily interrupted sleep because of pain. The orthopedic surgeon gave me two options, cortisone injections or a knee joint replacement which he doesn’t favor because at 58 I’m still in the “young” category. Since cortisone injections are not a sustainable long term solution I’m considering a replacement. I’m pretty much done with the pain and limp. My question is, what is a good strategy to prepare my body for surgery (before and after) to enhance the recovery process, using peptides (or other) and localized red light therapy? Any input from the community is highly appreciated.
Dr Reviews Grey Market Peptide Scams
Worth a view. Yes your Vendor source matters. There's been a few individuals in the forum recently claiming they are "experts" and have so-called "extensive knowledge" who have criticized posts like this about China grey market testing reviews. When challenged, they can't back up their position with any verifiable evidence. Any vendor whether their product is made in China or US should be able to provide COAs that can be confirmed with a reputable 3rd party testing laboratory. Here’s a link to industry group American Peptide Association on how to read a COA. https://americanpeptide.co/blogs/blog/how-to-read-a-peptide-certificate-of-analysis Be aware of fake COAs that can't be cross-checked with 3rd party labs. Not manufacturer test, but independent test. Recent Clinical Paper (link is for pre-print) "Evaluation of Research Grade Peptides Marketed Directly to Consumers Reveals Extensive Variability in Purity and Measured Abundance." https://www.preprints.org/manuscript/202604.1748 "A total of 6441 peptide samples across fourteen compounds, including BPC-157, cagrilintide, CJC-1295, GHK-Cu, ipamorelin, PT-141, retatrutide, semaglutide, sermorelin, survodutide, TB-500, tesamorelin, thymosin beta-4, and tirzepatide, were analyzed." "The main finding of the study, that 41.6% to 71.1% of gray market peptides failed fundamental safety standards..." "..measurable endotoxin contamination was present in 15% of samples."
4MG R + IGF2-LR3
Any thoughts on this scenario? It seems backwards to me, but I can also see the possibility that R and IGF2-LR3 are working in opposite directions when it comes to glucose. On 4mg R per week. Started 5/3 at 0.5 and titrated up to 4 where I have been since then. I have acomplished my weight loss goal down from 186.7 to 156.7 and body fat percentage down from 27.4 to 17.4. Now working on a little more lean muscle increase. I started IGF-LR3 on Monday at 20mcg sub-q. Been wearing a continuous blood glucose monitor. Taking mornings after strength training. First two days I ate my regular breakfast of greek yogurt and blueberries + protein but added a slice of multigrain bread with peanut butter and honey to avoid low blood sugar. That worked fine Monday and Tuesday and my glucose remained in the normal range consistant with last week pre IGF-LR3. This morning, I injected IGF-LR3 after my strength training but had my meal about 45 minutes or so AFTER the injection. I was expecting a dip in blood sugar but to my suprise, it rose to 168 mg/dl and then later after lunch it rose to 176 mg/dl. 2 hours after lunch it is back to 133 mg/dl. Normally, prior to IGF-LR3, the highest my glucose level would get would be 140 after a meal but usually is in the low 100's or high 90's. My A1C is 4.5.
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