I have seen a lot of people posting about the success or nasal delivery for Semax and Selank. This has intrigued me for to the fact that I love the idea of these compounds yet haven’t had the best of luck with them. Then I started seeing advertisements for NAD and and BPC157 using this method as a delivery vehicle. So… I started digging, bought some saline, some bottles, and dug out my Selank. So far I have made a Selank and a NAD nasal spray. I am about a week into my research, so things are still early. I really love the thought using a compound without the need to inject it. The Selank makes since due to the neurological effect being delivered to the blood stream so close to the target area. Since NAD is a systemic compound, I don’t believe it is hurting anything to use this delivery method. The only concerning thing to me is the fact that I am not getting the quantity of NAD with this delivery method and will take time, patience, practice to get the adjustment pinned down. I would like to hear what you think about the subject, have you tried this, where have you seen the benefits?

Most of us who have spent time researching mitochondrial health eventually run across two familiar names: SS-31 MOTS-c I've discussed both quite a bit. But recently I listened to Alex Kikel speak at a peptide conference, and he mentioned two compounds that immediately caught my attention: HDAP2 — as a possible next-generation alternative to SS-31. Mitochonic Acid — as something we may eventually hear discussed alongside, or potentially instead of, MOTS-c. So naturally, I was more than curious and started digging. I’d never heard of either and found there is actually quite a bit going on here. 🔥 HDAP2 — WHAT COMES AFTER SS-31? One of the primary jobs of SS-31 is helping protect and stabilize the inner membrane of our mitochondria. Think of that membrane as part of the machinery that allows the mitochondria to efficiently produce energy. When it becomes damaged or unstable, mitochondrial performance suffers. HDAP2 is being researched as another way of protecting and stabilizing that same critical mitochondrial structure. But this isn't just a molecule someone recently dreamed up. Researchers have already moved into animal studies. HDAP2 has been given systemically to mice and has demonstrated the ability to actually reach mitochondria in the targeted tissue. In models involving mitochondrial damage, researchers have reported: → better mitochondrial preservation → less cellular damage → improved cell survival → protection of mitochondrial function under stress One recent study involving damaged optic nerves was particularly interesting. Animals receiving HDAP2 retained dramatically more mitochondria in the injured nerves than untreated animals. Tells me there's enough here to keep watching. ⚡ MITOCHONIC ACID — THIS ONE REALLY GOT MY ATTENTION The second compound Kikel mentioned was Mitochonic Acid. Technically, this isn't a peptide at all. But forget the chemistry for a minute. What matters is what researchers are trying to accomplish with it. Mitochondria have an incredibly organized internal structure. Those little folds you've probably seen in every drawing of a mitochondrion aren't there by accident. They're where much of our cellular energy production takes place.